Researchers do precise gene therapy without a needle

L. James Lee

L. James Lee and his colleagues at Ohio State University have successfully inserted specific doses of an anti-cancer gene into individual leukemia cells to kill them without a needle. The technique uses electricity to “shoot” bits of therapeutic biomolecules through a tiny channel and into a cell in a fraction of a second.

They have dubbed the method “nanochannel electroporation” (NEP).

“NEP allows us to investigate how drugs and other biomolecules affect cell biology and genetic pathways at a level not achievable by any existing techniques,” said Lee, the Helen C. Kurtz Professor of Chemical and Biomolecular Engineering and director of the NSF Nanoscale Science and Engineering Center for Affordable Nanoengineering of Polymeric Biomedical Devices at Ohio State.

http://www.kurzweilai.net/researchers-do-precise-gene-therapy-without-a-needle

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